1364 Clifton Road, EUH, F147A
Atlanta, GA 30322
Director of Molecular Diagnostics Laboratory, Emory University Hospital
Director of Residency Programs, Emory University Hospital
Co-Director, Molecular Genetic Pathology Fellowship, Emory University School of Medicine
BS Biochemistry, Clemson University, 1985 - 1989
MD Medical University of South Carolina, 1989 - 1998
PhD Molecular And Cellular Biology, Medical University of South Carolina, 1989 - 1998
I am participating in a variety of research projects centered on translating basic science research into clinical practice. We have been investigating the role of virally encoded oncogenes in aggressive behavior of laryngeal papillomatosis, the clinical utility and implementation of pharmacogenetics, and the development of tests for diagnosis or prognosis in a variety of malignanacies.
Development of new clinical molecular diagnostic tests. Clinical application of pharmacognetics.
I am engaged in development of clinical pharmacogenetic testing and molecular tumor diagnostics, as well as overseeing day-to-day operations of the molecular diagnostics laboratory. I am also involved in the clinical interpretation of protein electrophoresis and autoimmunity testing.
First Prize Poster, Australasian Division of the International Academy of Pathology, Sydney, Australia, B. Amanuel, A.T. Deyrup, C.E. Hill, C. Foulks, A. Glasingame, S. Li, S.W. Weiss, Molecular Testing for Synovial Sarcoma, 2007
Outstanding Speaker Award, American Association for Clinical Chemistry, 2006
Golden Apple Teaching Award, 2004-2005
Alpha Omega Alpha, 1997
Faculty Scholarship Award, Clemson University, 1989
Norris Medal, Best All-Around Student, Clemson University, 1989
Summa Cum Laude, Clemson Univeristy, 1989
2004 Diplomate Anatomic and Clinical Pathology, American Board of Pathology
2005 Diplomate Molecular Genetic Pathology, American Board of Pathology & American Board of Medical Genetics
Cole JM, Schuetz AN, Hill CE, Nolte FS. 2009. Development and evaluation of a real-time PCR assay for detection of Klegsiella pnaumoniae carbapenemase genes. J Dlin Microbio. Feb; 47(2):322-6
Shehata, BM. Otto, KM. Sobol, SE. Stockwell, CA. Foulks, C. Hill, CE. 2008. The role of E2, E6, and E7 gene expression by human papilloma virus (HPV) and the aggressive behavior of recurrent laryngeal papillomatosis (RLP). Pediatr Devel Pathol, 11:118
Ahsanuddin, AN, Standish, MC, Caliendo, AM, Hill, CE, and Nolte, FS. 2008. Validation of an Epstein Barr viral load assay using the QIAGEN ARtus EBV TM PCR Analyte-specific Reagent, Am J Clin Path. Dec; 130(6):865-9
Deyrup, AT. Lee, VK. Hill, CE. Cheuk, W. Toh, HC. Kesavan, S. Chan, EW. Weiss, SW. Epstein-Barr virus-associated smooth muscle tumors are distinctive mesenchymal tumors reflecting multiple infection events: a clinicopathologic and molecular analysis of 29 tumors from 19 patients. Am J Surg Pathol. 2006 Jan;30(1):75-82.
Hill, CE. Harris, SB. Culler, EE. Zimring, JC. Nolte, FS. Caliendo, AM. Performance Characteristics of Two Real-Time PCR Assays for the Quantification of Epstein-Barr Virus DNA. Am J Clin Pathol. 2006;125:665-671.
Hill, CE. Duncan, A. Wirth, D. Nolte, FS. Detection and Identification of Cytochrome P-450 2C9 Alleles *1, *2, and *3 by High-Resolution Melting Curve Analysis of PCR Amplicons. Am J Clin Pathol 2006;125:584-591
Hill, CE. Caliendo, AM. Viral Load Testing. In: Molecular Microbiology: Diagnostic Principles and Applications. Eds: Persing, DH. Tenover FC. Versalovic J. Tang, Y-W. Unger, ER. Relman, DA. White TJ. ASM Press, 2004.
Hill, CE. Green, AM. Ingersoll, J. Easley, K. Nolte, FS. Caliendo, AM. Assessment of Agreement between the AMPLICOR HIV-1 MONITOR Test Versions 1.0 and 1.5. Journal of Clinical Microbiology. 42(1), 2004 Jan.
Fiebelkorn KR. Lee BG. Hill CE. Caliendo AM. Nolte FS. Clinical evaluation of an automated nucleic acid isolation system. Clinical Chemistry. 48(9):1613-5, 2002 Sep.
Folpe AL. Hill CE. Parham DM. O'Shea PA. Weiss SW. Immunohistochemical detection of FLI-1 protein expression: a study of 132 round cell tumors with emphasis on CD99-positive mimics of Ewing's sarcoma/primitive neuroectodermal tumor. American Journal of Surgical Pathology. 24(12):1657-62, 2000 Dec.
Philip AT. Amin MB. Tamboli P. Lee TJ. Hill CE. Ro JY. Intravesical adipose tissue: a quantitative study of its presence and location with implications for therapy and prognosis. American Journal of Surgical Pathology. 24(9):1286-90, 2000 Sep.
Davis A. Fields A. Hill C. Hanzlick R. Unavoidable outcomes vs misadventures. Autopsy Committee of the College of American Pathologists. Archives of Internal Medicine. 159(7):646-7, 1999 Apr 12.
Liu Y. Raghunathan K. Hill C. He Y. Bunni MA. Barredo J. Priest DG. Effects of antisense-based folypoly-gamma-glutamate synthetase down-regulation on reduced folates and cellular proliferation in CCRF-CEM cells. Biochemical Pharmacology. 55(12):2031-7, 1998 Jun 15.
Lenz HJ. Hill C. Danenberg KD. Leichman LL. Priest DG. Danenberg PV. Rapid quantitative PCR for determination of relative gene expressions in tissue specimens. PCR Methods & Applications. 4(5):305-8, 1995 Apr
Liu Y. Bhalla K. Hill C. Priest DG. Evidence for involvement of tyrosine phosphorylation in taxol-induced apoptosis in a human ovarian tumor cell line. Biochemical Pharmacology. 48(6):1265-72, 1994 Sep 15.
F.S. Nolte and C.E. Hill. 2006. Polymerase Chain Reaction and other Amplification Technology. In: Clinical Diagnosis and Management by Laboratory Methods, 21st ed. W.B. Saunders Co.
Caliendo AM and Hill CE, Human Immunodeficiency Virus Type 1. In: Molecular Diagnostics for the Clinical Laboratorian 2nd Edition. Eds. WB Coleman and GJ Tsongalis. Humana Press. pp. 453-459.
Hill, CE and Caliendo, AM. Viral Load Testing. In: Molecular Microbiology. Diagnostic Principles and Practice. 2004. 2nd Edition. Eds. DH Persing, FC Tenover, J Versalovic, Y-W Tang, ER Unger, DA Relman, TJ White. ASM Press. pp. 478-488.
Vitamin K Epoxide Reductase (VKORC1) Genotype Discrepancy Between Donor and Recipient in a Liver Transplant Patient: A Case Report, 2008. S.D. Melton, C. Foulks, C.E. Hill, H. Gebel. Association for Molecular Pathology, Grapevine, TX.
Performance Validation of BK Virus Nanogen v.2.0 Assay: Method Comparison to Nanogen v.1.0, 2008. C.L. Schmotzer, M.C. Standish, A.M. Caliendo, C.E. Hill. Association for Molecular Pathology, Grapevine, TX.
S. Melton, C. Cohen, N. Fanaian, T. Pillen, J. Wang, B. Shehata, C.E. Hill. 2007. Epstein-Barr Virus PCR and Epstein-Barr Virus-Encoded RNA in-situ Hybridization as Diagnostic Aids for Post-Transplant Lymphoproliferative Disorder, Association for Molecular Pathology, Los Angeles, CA.
J.M. Cole, A.N. Schuetz, C.E. Hill, F.S. Nolte. 2007. Development of a Real-Time Assay for the Detection and Characterization of Klebsiella Pneumoniae Carbapenemases, Association for Molecular Pathology, Los Angeles, CA.
L. Sanii, C. Foulks, K. Mann, C. Hill. 2007. Investigation of the Use of Anti-CD15 Magnetic Beads to Enhance Detection of the V617F Mutation of JAK2, Association for Molecular Pathology, Los Angeles, CA.
B. Amanuel, A.T. Deyrup, C.E. Hill, C. Foulks, A. Blasingame, S. Li, S.W. Weiss. 2007. Molecular Testing for Synovial Sarcoma, Australasian Division of the International Academy of Pathology, Sydney, Australia.
J.M. Cole, C. Foulks, H. Radziewicz, F.S. Nolte, C.E. Hill. 2006. Clinical Laboratory Comparison of the Third Wave Technologies Invader and the Abbott HCV Genotype Analyte-Specific Reagents, Association for Molecular Pathology, Orlando, FL
S.D. Melton, C. Foulks, C.E. Hill. 2006. High Resolution Amplicon Melting Curve Analysis of C-kit for Mutations in Cutaneous Mastocytosis, Systemic Mastocytosis, and Gastrointestinal Stromal Tumors. Association for Molecular Pathology, Orlando, FL
Park, SI. Winton, EF. Mann, KP. Hill, CE. 2006. High Resolution Amplicon Melting Curve Analysis: A Sensitive And Rapid Method To Detect The Janus Kinase 2 (Jak2) Gene Association for Molecular Pathology, Orlando, FL.
Hill, CE. Duncan, A. Nolte, FS. Determination of CYP2C9 Genotype by High Resolution Amplicon Melting Curve Analysis Using LCGreen I. Association for Molecular Pathology, Orlando, FL, 2003.
Subtil, A. Hill, CE. Nolte, FS. Mann, KP. Clinical Validation of the LightCycler t(15;17) Real-Time RT-PCR Kit for the Detection of PML-RAR¿ RNA. Association for Molecular Pathology, Orlando, FL, 2003.
Hill, CE. Green, AM. Ingersoll, J. Nolte, FS. Caliendo AM. Comparison of Versions 1.0 and 1.5 of the AMPLICOR HIV -1 MONITOR Test, Association For Molecular Pathology, Dallas, TX, 2002.
Hill CE. Folpe AL. Parham DM. O'Shea PA. Weiss SW. Immunohistochemical detection of FLI-1 protein expression: a study of 132 round cell tumors with emphasis on CD99-positive mimics of Ewing's sarcoma/primitive neuroectodermal tumor. United States and Canadian Academy of Pathology, New Orleans, LA 2000
Hill, C. E., Lankford, K. V., Brown, W. V., Duncan, A., and Hillyer, C. D. Plasma Exchange (TPE) for Elevated Lipoprotein(a) (Lp(a)) in a Patient with Xanthoma Disseminatum (XD). American Association of Blood Banks, San Francisco, CA, 1999.
Priest, D. G., Liu, Y., Raghunathan, K., Hill, C., He, Y., Barredo, J. C., and Bunni, M. A. Effect of folylpoly-¿-gluatmate synthase down-regulation on reduced folate accumulation and cellular proliferation in a human T-lymphoblastic leukemic cell line. American Association for Cancer Research, New Orleans, LA, 1998.
Hill, C. E. and Priest, D. G. Response of thymidylate synthase message to methotrexate in a human leukemic cell line. South Carolina Statewide Research Conference, Charleston, SC, 1996.
Hill, C. E. and Priest, D. G. Elevation of thymidylate synthase protein in response to antifolates in a human leukemic cell line. Gordon Conference on Chemotherapy of Experimental and Clinical Cancer, New London, NH, 1995.
Hill, C. E. and Priest, D. G. Elevation of thymidylate synthase in response to methotrexate and tomudex in a human leukemic cell line. American Association for Cancer Research, Washington, D. C., 1995.
Liu, Y., Bhalla, K., Hill, C., and Priest, D. Evidence for involvement of tyrosine phosphorylation in taxol induced apoptosis in a human ovarian tumor cell line. American Association for Cancer Research, San Francisco, CA, 1994.