Profile of a Pathology Faculty Member

Pathology Faculty Photo

Alyssa Krasinskas, MD

Professor
Pathology & Laboratory Medicine

Other Appointments/Positions

  • Director, Surgical Pathology, Pathology and Laboratory Medicine, Emory University

Pathology Division(s):
Anatomic Pathology

Email Address:   akrasin@emory.edu

Education:

BA   Clark University, Worcester, MA, - 1990
MD   University of Rochester School of Medicine and Dentistry, - 1994
Resident   AP/CP Residency, Department of Pathology and Laboratory Medicine, University of Pennsylvania Medical Center, Philadelphia, PA, - 2001
Fellow   GI, Liver and Surgical Pathology Fellow, Department of Pathology and Laboratory Medicine, University of Pennsylvania Medical Center, Philadelphia, PA, - 2002

Research Interests:

- Pancreatic cancer Molecular pathogenesis Treatment effect
- Ampullary cancer Classification and staging of ampullary tumors Molecular pathogenesis
- Peritoneal disease Mesotheliomas and mucinous adenocarcinomas
- Liver allograft rejection

Clinical Focus:

GI pathology (resections and biopsies) Pancreaticobiliary pathology Hepatic pathology (including liver transplantation) Director of Surgical Pathology Director of GI / Liver Pathology Fellowship

Honors / Awards:

  • The Rodger C. Haggitt Gastrointestinal Pathology Society Distinguished Service Award, 2017
  • Emory Pathology Faculty Mentorship Award, 2016
  • Rodger C. Haggitt Gastrointestinal Pathology Society Award to Chad Rund for Best Presentation by a Resident/Fellow at the annual USCAP meeting (Mentor and Senior Author), 2007
  • The H.T. Enterline Fellowship Award for Excellence in Diagnostic Skills and Commitment to Teaching and Scholarly Activity, University of Pennsylvania, 2002
  • American Society of Transplantation Young Investigator Award, 1999
  • International Society of Heart and Lung Transplantation Research Fellowship: The Role of Bone Marrow-Derived Elements in Allograft Rejection ($25,000), 1998
  • George H. Whipple, M.D. Academy of Medicine Award for Contributing to the Progress of Medicine, University of Rochester School of Medicine and Dentistry, 1993
  • Victor M. Emmel Award for Excellence in Histology, University of Rochester School of Medicine and Dentistry, 1991

Selected/Most Recent Publications:

Click here to view all publications

Published and Accepted Research Articles -

  • Parslow TG, Adsay NV, Krasinskas AM, Roback JD. Impacts of new concepts and technologies on the practice of diagnostic pathology: an Emory University perspective. Arch Pathol Lab Med. 2017 Mar;141(3):325-28
  • Srivastava A, Appelman H, Goldsmith JD, Davison JM, Hart J, Krasinskas AM. The use of ancillary stains in the diagnosis of Barrett esophagus and Barrett esophagus-associated dysplasia: recommendations from the Rodger C. Haggitt Gastrointestinal Pathology Society. Am J Surg Pathol. 2017 May;41(5):e8-e21.
  • Gonzalez RS, Adsay V, Graham RP, Shroff SG, Feely MM, Drage MG, Lewin DN, Swanson EA, Yantiss RK, Bagci P, Krasinskas AM. Massive gastric juvenile-type polyposis: a clinicopathologic analysis of 22 cases. Histopathology. 2017 May;70(6):918-28.
  • Zhelnin K, Xue Y, Quigley B, Reid MD, Choi H, Memis B, Adsay V, Krasinskas AM. Nonmucinous Biliary Epithelium Is a Frequent Finding and Is Often the Predominant Epithelial Type in Mucinous Cystic Neoplasms of the Pancreas and Liver. Am J Surg Pathol. 2017 Jan;41(1):116-20.
  • Xue Y, Vanoli A, Balci S, Reid MM, Saka B, Bagci P, Memis B, Choi H, Ohike N, Tajiri T, Muraki T, Quigley B, El-Rayes BF, Shaib W, Kooby D, Sarmiento J, Maithel SK, Knight JH, Goodman M, Krasinskas AM, Adsay V. Non-ampullary-duodenal carcinomas: clinicopathologic analysis of 47 cases and comparison with ampullary and pancreatic adenocarcinomas. Mod Pathol. 2017 Feb;30(2):255-66.
  • Krasinskas AM, Oakley GJ, Bagci P, Jang KT, Kuan SF, Reid MD, Erbarut I, Adsay V. "Simple Mucinous Cyst" of the Pancreas: A Clinicopathologic Analysis of 39 Examples of a Diagnostically Challenging Entity Distinct From Intraductal Papillary Mucinous Neoplasms and Mucinous Cystic Neoplasms. Am J Surg Pathol. 2017 Jan;41(1):121-27.
  • Lawless ME, Toweill DL, Jewell KD, Jain D, Lamps L, Krasinskas AM, Swanson PE, Upton MP, Yeh MM. Massive gastric juvenile polyposis: a clinicopathologic study using SMAD4 immunohistochemistry. Am J Clin Pathol. 2017 Mar 18. doi: 10.1093/ajcp/aqx015 [Epub ahead of print]
  • Jin R, Krasinskas A, Le NA, Konomi JV, Holzberg J, Romero R, Vos MB. Association between plasminogen activator inhibitor-1 and severity of liver injury and cardiovascular risk in children with non-alcoholic fatty liver disease. Pediatr Obes. 2016 Oct 20. doi: 10.1111/ijpo.12183. [Epub ahead of print] PMID: 27764892
  • Saka B, Balci S, Basturk O, Bagci P, Postlewait LM, Maithel S, Knight J, El-Rayes B, Kooby D, Sarmiento J, Muraki T, Oliva I, Bandyopadhyay S, Akkas G, Goodman M, Reid MD, Krasinskas A, Everett R, Adsay V. Pancreatic Ductal Adenocarcinoma is Spread to the Peripancreatic Soft Tissue in the Majority of Resected Cases, Rendering the AJCC T-Stage Protocol (7th Edition) Inapplicable and Insignificant: A Size-Based Staging System (pT1: ¿2, pT2: >2-¿4, pT3: >4 cm) is More Valid and Clinically Relevant. Ann Surg Oncol. 2016 Jun;23(6):2010-8.
  • Muraki T, Reid MD, Basturk O, Jang KT, Bedolla G, Bagci P, Mittal P, Memis B, Katabi N, Bandyopadhyay S, Sarmiento JM, Krasinskas A, Klimstra DS, Adsay V. Undifferentiated Carcinoma With Osteoclastic Giant Cells of the Pancreas: Clinicopathologic Analysis of 38 Cases Highlights a More Protracted Clinical Course Than Currently Appreciated. Am J Surg Pathol. 2016 Sep;40(9):1203-16.
  • Reid MD, Basturk O, Shaib WL, Xue Y, Balci S, Choi HJ, Akkas G, Memis B, Robinson BS, El-Rayes BF, Staley CA, Staley CA, Winer JH, Russell MC, Knight JH, Goodman M, Krasinskas AM, Adsay V. Adenocarcinoma ex-goblet cell carcinoid (appendiceal-type crypt cell adenocarcinoma) is a morphologically distinct entity with highly aggressive behavior and frequent association with peritoneal/intra-abdominal dissemination: an analysis of 77 cases. Mod Pathol. 2016 Oct;29(10):1243-53.
  • Halenda KM, Kudchadkar RR, Lawson DH, Kies DD, Zhelnin KE, Krasinskas AM, Grossniklaus HE. Reduction of Nodular Growth Pattern of Metastatic Uveal Melanoma after Radioembolization of Hepatic Metastases. Ocul Oncol Pathol. 2016 Apr;2(3):160-5.
  • Reid MD, Balci S, Ohike N, Xue Y, Kim GE, Tajiri T, Memis B, Coban I, Dolgun A, Krasinskas AM, Basturk O, Kooby DA, Sarmiento JM, Maithel SK, El-Rayes BF, Adsay V. Ampullary carcinoma is often of mixed or hybrid histologic type: an analysis of reproducibility and clinical relevance of classification as pancreatobiliary versus intestinal in 232 cases. Mod Pathol. 2016 Dec;29(12):1575-85
  • Gonzalez RS, Bagci P, Basturk O, Reid MD, Balci S, Knight JH, Kong SY, Memis B, Jang KT, Ohike N, Tajiri T, Bandyopadhyay S, Krasinskas AM, Kim GE, Cheng JD, Adsay NV. Intrapancreatic distal common bile duct carcinoma: Analysis, staging considerations, and comparison with pancreatic ductal and ampullary adenocarcinomas. Mod Pathol. 2016 Nov;29(11):1358-69. doi: 10.1038/modpathol.2016.125.
  • Singhi AD, Krasinskas AM, Choudry HA, Bartlett DL, Pingpank JF, Zeh HJ, Luvison A, Fuhrer K, Bahary N, Seethala RR, Dacic S. The prognostic significance of BAP1, NF2, and CDKN2A in malignant peritoneal mesothelioma. Mod Pathol. 2016 Jan;29(1):14-24.

Book Chapters -

  • Krasinskas A, Pawlik TM, Mino-Kenudson M and Vauthey JN. Distal bile duct. In: AJCC Cancer Staging Manual. 8th ed. Springer, New York, NY. 2017; 317-326.
  • Quigley B and Krasinskas AM. Small Intestine, Appendix, Colorectum, and Anus. In: Essentials of Anatomic Pathology. 4th ed. Springer, New York, NY. 2016; 1907-1944.
  • Krasinskas AM. Developmental disorders of the gallbladder, extrahepatic biliary tract and pancreas. In: Goldblum JR and Odze R (eds). Surgical Pathology of the GI Tract, Liver, Biliary Tract and Pancreas. 3rd ed. Elsevier, Philadelphia, PA. 2015; 980-994.
  • Robinson B and Krasinskas AM. Pathology of premalignant and malignant disease of the esophagus. In: Saba NF and El-Rayes BF (eds). Esophageal cancer Prevention, Diagnosis and Therapy. Springer, New York, NY. 2015; 41-60.
  • Krasinskas AM and Goldsmith JD. Immunohistology of the Gastrointestinal Tract. In: Dabbs DA (ed). Diagnostic Immunohistochemistry: Theranostic and Genomic Applications. 4th ed. Elsevier, Philadelphia, PA. 2013; 508-539.