Profile of a Pathology Faculty Member

Pathology Faculty Photo

James C Ritchie, PhD

Clinical Chemistry

Professor
Pathology & Laboratory Medicine

Other Appointments/Positions

  • Director, Core Laboratory, Emory Crawford Long Hospital
  • Associate Director, Core and Toxicology Laboratories, Emory University Hospital

Pathology Division(s):
Clinical Pathology
Experimental Pathology
Email Address:   jritchi@emory.edu

Education:

BS   Bachelor of Science, Zoology, The University of Michigan, 1970 -
PhD   Doctor of Philosophy, Pharmacology, Duke University, 1995 -
Master   Master of Public Health, Epidemiology,The University of Michigan, 1976 -

Research Interests:

My research laboratory is engaged in determing whether the regulation of extracellular peptidase activity plays a significant role in neuropeptide action. In another project, we are focusing on the pharmacokinetics/pharmacodynamics of antidepressants and anti-seizure medications during pregnancy. Finally I am actively pursuing investigations into the use of proteomics as a clinical diagnostic tool.

Honors / Awards:

  • Travel Fellowship, Summer Neuropeptide Meeting, 1995
  • Endocrine Society Summer Student Fellowship, 1989

Specialty Boards:

  • Diplomate Diplomate, American Board of Clinical Chemistry

Selected/Most Recent Publications:

Click here to view all publications

Published and Accepted Research Articles -

  • Pomara, N., Willoughby, L.M., Ritchie, J.C., Sidtis, J.J., Greenblatt, D.J., Nemeroff, C.B. (2004). Interdose elevation in plasma cortisol during chronic treatment with alprazolam but not lorazepam in the elderly. Neuropsychopharmacology. 29(3):605-11, Mar.
  • Hostetter, A.L., Stowe, Z.N., Cox, M., Ritchie, J.C. (2004). A novel system for the determination of antidepressant concentrations in human breast milk. Therapeutic Drug Monitoring 26: 47-52, Feb.
  • Newport, D.J., Heim, C., Owens, M.J., Ritchie, J.C., Ramsey, C.H., Bonsall, R., Miller, A.H., Nemeroff, C.B. (2003). Cerebrospinal fluid corticotropin-releasing factor (CRF) and vasopressin concentrations predict pituitary response in the CRF stimulation test: a multiple regression analysis. Neuropsychopharmacology. 28(3):569-76, Mar.
  • Ritchie, J.C., Davis, T.P., Nemeroff, C.B. (2003). Action of three ectopeptidases on corticotropin-releasing factor: Metabolism and functional aspects. Neuropsychopharmacology 28: 22-33, Jan.
  • Stowe, Z.N., Hostetter, A.L., Owens, M.J., Ritchie, J.C., Sternberg, K., Cohen, L.S., Nemeroff, C.B. (2003). The pharmacokinetics of sertraline excretion into human breast milk: determinants of infant serum concentrations. Journal of Clinical Psychiatry. 64(1):73-80, Jan.
  • Rose, J.E., Behm, F.M., Ramsey, C., Ritchie, J.C.. (2001). Platelet monoamine oxidase, smoking cessation and tobacco withdrawal symptoms. Nicotine and Tobacco Research 3: 383-390.
  • Slotkin, T.A., Seidler, F.J., Ritchie, J.C. (2000). Regional differences in brain monoamine oxidase subtypes in an animal model of geriatric depression: Effects of olfactory bulbectomy in young versus aged rats. Brain Research 882:149-154.
  • Cassidy, F., Ritchie, J.C., Verghese, K., Carroll, B.J. (2000). Dexamethasone metabolism in dexamethasone suppression test suppressors and nonsuppressors. Biol Psychiatry. 47:677-680.
  • Stowe, Z.A., Cohen, L.S., Hostetter, A., Ritchie, J.C., Owens, M.J., Nemeroff, C.B. (2000). Paroxetine in human breast milk and nursing infants. Amer. Jour. Psychiatr. 157:2:185-189.
  • McCune, J.S., Hawke, R.L., LeCluyse, E.L., Gillenwater, H.H., Hamilton, G., Ritchie, J.C., Lindley, C. (2000). In-vivo and in-vitro induction of human cytochrome P4503A4 by dexamethasone. Clin Pharmacol Ther. 68:356-366.
  • Weber, C.J. and Ritchie, J.C. (1999). Retrospective analysis of sequential changes in serum intact parathyroid hormone (PTH) levels during conventional parathyroid exploration. Surgery 126:1139-1144.
  • Ritchie, J.C. (1999). Homocysteine and neuropsychiatric disorders. Diagnostic Endo, Immuno, and Metab., 17:35-38.
  • Slotkin, T.A., Seidler, F.J., Ritchie, J.C. (1998). Effects of aging and glucocorticoid treatment on monoamine oxidase subtypes in rat cerebral cortex: Therapeutic Implications. Brain Research Bulletin, 47:345-348.
  • Radke, J.M., Owens, M.J., Ritchie, J.C., Nemeroff, C.B. (1998). Atypical antipsychotic drugs selectively increase neurotensin efflux in dopamine terminal regions. Proc. Natl. Acad. Sci. (USA), 95:11462-11464.
  • Cassidy, F., Ritchie, J.C., Carroll, B.J. (1998). Plasma dexamethasone concentrations and cortisol response during manic episodes. Biological Psychiatry, 43:747-754.

Book Chapters -

  • Owens, M.J., and Ritchie, J.C. (1999). Clinical Neurochemistry. In: The Neurobiological Foundation of Mental Illness, (Charney, D.S., Nestler, E.J., Bunney, B.S., Eds.), Oxford University Press, New York , NY.
  • Owens, M.J., and Ritchie, J.C. (1999). Clinical Neurochemistry. In: The Neurobiological Foundation of Mental Illness, (Charney, D.S., Nestler, E.J., Bunney, B.S., Eds.), Oxford University Press, New York , NY.
  • Ritchie, J.C., Bissette, G. (1992). Radioimmunoassay methods. In: Neuroendocrinology, (Nemeroff, C.B., Ed), CRC Press, Boca Raton, Florida, 39-50.
  • Ritchie, J.C., Bissette, G. (1992). Radioimmunoassay methods. In: Neuroendocrinology, (Nemeroff, C.B., Ed), CRC Press, Boca Raton, Florida, 39-50.
  • Krishnan, K.R.R., Doraiswamy, P.M., Venkataraman, S., Reed, D., Ritchie, J.C. (1991). Current concepts in hypotalamo pituitary adrenal axis regulation. In: Stress, Neuropeptides, and Systemic Disease, (McCubbin, J.A., Kaufmann, P.G., and Nemeroff, C.B., Eds.), Academic Press, Orlando, Florida, 19-35.
  • Ritchie, J.C., Nemeroff, C.B. (1991). The hypothalamic pituitary adrenal axis and depression. In: Stress, Neuropeptides, and Systemic Disease, (McCubbin, J.A., Kaufmann, P.G., and Nemeroff, C.B., Eds.), Academic Press, Orlando, Florida, 181-197.
  • Krishnan, K.R.R., Doraiswamy, P.M., Venkataraman, S., Reed, D., Ritchie, J.C. (1991). Current concepts in hypotalamo pituitary adrenal axis regulation. In: Stress, Neuropeptides, and Systemic Disease, (McCubbin, J.A., Kaufmann, P.G., and Nemeroff, C.B., Eds.), Academic Press, Orlando, Florida, 19-35.
  • Ritchie, J.C., Nemeroff, C.B. (1991). The hypothalamic pituitary adrenal axis and depression. In: Stress, Neuropeptides, and Systemic Disease, (McCubbin, J.A., Kaufmann, P.G., and Nemeroff, C.B., Eds.), Academic Press, Orlando, Florida, 181-197.
  • Krishnan, K.R.R., Ritchie, J.C., Manepalli, A.N., Venkataranman, S., France, R.D., Nemeroff, C.B., Carroll, B.J. (1988). What is the relationship between plasma ACTH and plasma cortisol in normal humans and depresssed patients? In: The Hypothalamic-Pituitary-Adrenal Axis, (Schatzberg, A.F. and Nemeroff, C.B., Eds.), Raven Press, New York, 115-132.
  • Krishnan, K.R.R., Ritchie, J.C., Manepalli, A.N., Venkataranman, S., France, R.D., Nemeroff, C.B., Carroll, B.J. (1988). What is the relationship between plasma ACTH and plasma cortisol in normal humans and depresssed patients? In: The Hypothalamic-Pituitary-Adrenal Axis, (Schatzberg, A.F. and Nemeroff, C.B., Eds.), Raven Press, New York, 115-132.
  • Kilts, C.D., Johnson, K.L., Ritchie, J.C. (1987). Analytical and methodological considerations in the study of the HPA Axis. In: The Hypothalamic-Pituitary-Adrenal Axis, (Schatzberg, A.F. and Nemeroff, C.B., Eds.), Raven Press, New York, 37-53.
  • Kilts, C.D., Johnson, K.L., Ritchie, J.C. (1987). Analytical and methodological considerations in the study of the HPA Axis. In: The Hypothalamic-Pituitary-Adrenal Axis, (Schatzberg, A.F. and Nemeroff, C.B., Eds.), Raven Press, New York, 37-53.
  • Krishnan, K.R.R., Nemeroff, C.B., Manepalli, A.N., France, R.D., Ritchie, J.C., Carroll, B.J. (1986). Physiology of Human HPA regulation in depression. In: Biological Psychiatry, (Shagass C., et al, Eds.), Elsevier, New York, 808-810.
  • Krishnan, K.R.R., Nemeroff, C.B., Manepalli, A.N., France, R.D., Ritchie, J.C., Carroll, B.J. (1986). Physiology of Human HPA regulation in depression. In: Biological Psychiatry, (Shagass C., et al, Eds.), Elsevier, New York, 808-810.

Other Publications -

  • Ritchie, J.C., Whooley, M.A., Mullins, R.E. (2002) Evaluation of Two Extended Range CRP Assays. 18th International Congress of Clinical Chemistry, Kyoto, Japan.
  • Ritchie, J.C., Whooley, M.A., Mullins, R.E. (2002) Evaluation of Two Extended Range CRP Assays. 18th International Congress of Clinical Chemistry, Kyoto, Japan.
  • Ritchie, J.C. and Ramsey, C. (2001) Pretreatment with High Dose CRF Increases Subsequent CRF Catabolism in Rat Pituitary Cultures. Society for Neuroscience Annual Meeting SanDiego, CA.
  • Ritchie, J.C. and Ramsey, C. (2001) Pretreatment with High Dose CRF Increases Subsequent CRF Catabolism in Rat Pituitary Cultures. Society for Neuroscience Annual Meeting SanDiego, CA.
  • Ritchie, J.C., Mullins, R.E.; Benson, E, Davis, T. (2001) Comparison of Five Assays for Homocysteine. American Association for Clinical Chemistry Annual Meeting, Chicago, IL.
  • Ritchie, J.C., Mullins, R.E.; Benson, E, Davis, T. (2001) Comparison of Five Assays for Homocysteine. American Association for Clinical Chemistry Annual Meeting, Chicago, IL.
  • Ritchie, J.C., Slotkin, T.A., Seidler, F.J. (1998). Effects of aging and glucocorticoid treatment on monoamine oxidase subtypes in rat cerebral cortex: Therapeutic Implications. Society for Neuroscience Abstracts, 24, 28th Annual Meeting, Los Angeles, CA.
  • Ritchie, J.C., Tuten, T., Jerkunica, I., Zhang, H., Sgoutas, D.S., Mullins, R.E. (1998). Evaluation of the Cobas-Integra for routine lipid testing. Clin Chem, 44(6): A78.
  • Ritchie, J.C., Slotkin, T.A., Seidler, F.J. (1998). Effects of aging and glucocorticoid treatment on monoamine oxidase subtypes in rat cerebral cortex: Therapeutic Implications. Society for Neuroscience Abstracts, 24, 28th Annual Meeting, Los Angeles, CA.
  • Ritchie, J.C., Mullins, R.E., Tuten, T., Zhang, H., Jerkunica, I. (1998). Evaluation of the DAU lysergic acid diethylamide (LSD) assay on the Cobas-Integra. Clin Chem, 44(6): A86.
  • Ritchie, J.C., Tuten, T., Jerkunica, I., Zhang, H., Sgoutas, D.S., Mullins, R.E. (1998). Evaluation of the Cobas-Integra for routine lipid testing. Clin Chem, 44(6): A78.
  • Ritchie, J.C., Mullins, R.E., Tuten, T., Zhang, H., Jerkunica, I. (1998). Evaluation of the DAU lysergic acid diethylamide (LSD) assay on the Cobas-Integra. Clin Chem, 44(6): A86.
  • Ritchie, J.C., Tuten, T., Jerkunica, I., Zhang, H., Mullins, R.E. (1997). Evaluation of the Cobas-Integra for drugs of abuse testing. Clin Chem, 43(6): S217.
  • Mullins, R.E., Jerkunica, I., Ritchie, J.C., Tuten, T. (1997). HbA1c measurements by immunoassay on the Cobas-Integra. Clin Chem, 43(6): S154.
  • Ritchie, J.C., Tuten, T., Jerkunica, I., Zhang, H., Mullins, R.E. (1997). Evaluation of the Cobas-Integra for drugs of abuse testing. Clin Chem, 43(6): S217.
  • Mullins, R.E., Jerkunica, I., Ritchie, J.C., Tuten, T. (1997). HbA1c measurements by immunoassay on the Cobas-Integra. Clin Chem, 43(6): S154.
  • Ritchie, J.C., Zhang, W. (1996). Modification of the BioRad antidepressant methodology to measure the serotonin reuptake inhibitors. Clin Chem, 42(6): S222, 48th Annual Meeting, Chicago, IL.
  • Ritchie, J.C., Zhang, W. (1996). Modification of the BioRad antidepressant methodology to measure the serotonin reuptake inhibitors. Clin Chem, 42(6): S222, 48th Annual Meeting, Chicago, IL.
  • Kim, D.K., Kim, B.L., Yu, B.H., Hong, K.S., Ritchie, J.C., Austin, S., Carroll, B.J. (1995). Rate-sensitive glucocorticoid feedback inhibition in normal humans and depressed patients. Society for Neuroscience Abstracts, 21(2): 873, 25th Annual Meeting, San Diego, CA.
  • Ritchie, J.C., Nemeroff, C.B. (1995). Effect of three ectopeptidases on corticotropin-releasing factor: Metabolism and functional aspects. Society for Neuroscience Abstracts, 21(1): 761, 25th Annual Meeting, San Diego, CA.
  • Ritchie, J.C., Nemeroff, C.B. (1995). Effect of three ectopeptidases on corticotropin-releasing factor: Metabolism and functional aspects. Society for Neuroscience Abstracts, 21(1): 761, 25th Annual Meeting, San Diego, CA.
  • Kim, D.K., Kim, B.L., Yu, B.H., Hong, K.S., Ritchie, J.C., Austin, S., Carroll, B.J. (1995). Rate-sensitive glucocorticoid feedback inhibition in normal humans and depressed patients. Society for Neuroscience Abstracts, 21(2): 873, 25th Annual Meeting, San Diego, CA.
  • Ritchie, J.C., Sundar, K.S., Nemeroff, C.B. (1994). Effect of specific peptidase inhibitors on CRF induced ACTH release in cultured rat pituitary cells. Society of Neuroscience Abstracts, 20(1), 447, 24th Annual Meeting, Miami Beach, FL.
  • Ritchie, J.C., Sundar, K.S., Nemeroff, C.B. (1994). Effect of specific peptidase inhibitors on CRF induced ACTH release in cultured rat pituitary cells. Society of Neuroscience Abstracts, 20(1), 447, 24th Annual Meeting, Miami Beach, FL.
  • Ritchie, J.C., Sundar, K.S., Nemeroff, C.B. (1994). Effect of specific peptidase inhibitors on CRF induced ACTH release in cultured rat pituitary cells. Society of Neuroscience Abstracts, 20(1), 447, 24th Annual Meeting, Miami Beach, FL.
  • Akers, L.C., Ritchie, J.C., Orsulak, P.J. (1993). Determination of salivary cortisol using a modification of the Abbott TDx serum cortisol assay. Clin Chem, 6:1255.
  • Ritchie, J.C., Nemeroff, C.B. (1993). Corticotropin releasing factor degradation by purified peptidases. Society of Neuroscience Abstracts, 19(2):1363, 23rd Annual Meeting, Washington, D.C.
  • Ritchie, J.C., Nemeroff, C.B. (1993). Corticotropin releasing factor degradation by purified peptidases. Society of Neuroscience Abstracts, 19(2):1363, 23rd Annual Meeting, Washington, D.C.
  • Akers, L.C., Ritchie, J.C., Orsulak, P.J. (1993). Determination of salivary cortisol using a modification of the Abbott TDx serum cortisol assay. Clin Chem, 6:1255.
  • Hayden-Hixson, D.M., White, N., Ritchie, J.C., Nemeroff, C.B. (1992). Neonatal handling: Effects on spatial memory, basal corticosterone levels, and hippocampal function. Society Neuroscience Abstracts, 18(2):1426, 22nd Annual Meeting, Annaheim, California.
  • Bragg, C., Ritchie, J.C., Carroll, B.J., Breitner, J.C.S. (1992). A matched twin study of DHEA and DHEA-S in alzheimer's disease. Biological Psychiarty, 31:201A.
  • Hayden-Hixson, D.M., White, N., Ritchie, J.C., Nemeroff, C.B. (1992). Neonatal handling: Effects on spatial memory, basal corticosterone levels, and hippocampal function. Society Neuroscience Abstracts, 18(2):1426, 22nd Annual Meeting, Annaheim, California.
  • Bragg, C., Ritchie, J.C., Carroll, B.J., Breitner, J.C.S. (1992). A matched twin study of DHEA and DHEA-S in alzheimer's disease. Biological Psychiarty, 31:201A.
  • Ritchie, J.C., Gupta, S.K., Carroll, B.J., Krishnan, K.R.R. (1991). Towards a pharmacokinetic pharmacodynamic model of plasma dexamethasone concentration during the DST. Biological Psychiatry, 29(suppl): 725S.
  • Owens, M.J., Ritchie, J.C., Nemeroff, C.B. (1991). THDOC decreases plasma corticosterone concentrations via a non glucocorticoid mechanism. Society for Neuroscience Abstracts, 17(2):1343, 21st Annual Meeting, New Orleans, Louisiana.
  • Owens, M.J., Ritchie, J.C., Nemeroff, C.B. (1991). THDOC decreases plasma corticosterone concentrations via a non glucocorticoid mechanism. Society for Neuroscience Abstracts, 17(2):1343, 21st Annual Meeting, New Orleans, Louisiana.
  • Ritchie, J.C., Owens, M.J., Nemeroff, C.B. (1991). Corticotropin releasing factor metabolism in the rat hypothalamus. Society for Neuroscience Abstracts, 17(1): 404, 21st Annual Meeting, New Orleans, Louisiana.
  • Ritchie, J.C., Bragg, D.C., White, N.R., Krishnan, K.R.R., Carroll, B.J. (1991). Plasma vasopressin, cortisol, and ACTH baseline levels in depression. Neuroendocrinology Letters, 13:208.
  • Ritchie, J.C., Bragg, D.C., White, N.R., Krishnan, K.R.R., Carroll, B.J. (1991). Plasma vasopressin, cortisol, and ACTH baseline levels in depression. Neuroendocrinology Letters, 13:208.
  • Ritchie, J.C., Gupta, S.K., Carroll, B.J., Krishnan, K.R.R. (1991). Towards a pharmacokinetic pharmacodynamic model of plasma dexamethasone concentration during the DST. Biological Psychiatry, 29(suppl): 725S.
  • Ritchie, J.C., Owens, M.J., Nemeroff, C.B. (1991). Corticotropin releasing factor metabolism in the rat hypothalamus. Society for Neuroscience Abstracts, 17(1): 404, 21st Annual Meeting, New Orleans, Louisiana.
  • Reed, D., Ritchie, J.C., Carroll, B.C., et al. (1990). Implications of simultaneous monitoring of plasma dexamethasone levels for the DST. Neuroendocrinology Letters, 12(4):261; XXI Congress of the International Society of Psychoneuroendocrinology, Buffalo/Niagara Falls, New York.
  • Vargas, M.A., Owens, M.J., Ritchie, J.C., Nemeroff, C.B. (1990). Time-course of action of the triazolobenzodiazepine, alprazolam, on HPA axis function in rats. Society for Neuroscience Abstracts, 16(1):92, 20th Annual Meeting, St. Louis, Missouri.
  • Clerpial, M.A., Grobin, A.C., Hargrove, E.F., McLean, K.P., Ritchie, J.C., et al. (1990). Elevated dorsal noradrenergic bundle turnover and plasma corticosterone responses to stress in rats selectively bred for high swim test activity. Society for Neuroscience Abstracts, 16(1): 165, 20th Annual Meeting, St. Louis, Missouri.
  • Clerpial, M.A., Grobin, A.C., Hargrove, E.F., McLean, K.P., Ritchie, J.C., et al. (1990). Elevated dorsal noradrenergic bundle turnover and plasma corticosterone responses to stress in rats selectively bred for high swim test activity. Society for Neuroscience Abstracts, 16(1): 165, 20th Annual Meeting, St. Louis, Missouri.
  • Vargas, M.A., Owens, M.J., Ritchie, J.C., Nemeroff, C.B. (1990). Time-course of action of the triazolobenzodiazepine, alprazolam, on HPA axis function in rats. Society for Neuroscience Abstracts, 16(1):92, 20th Annual Meeting, St. Louis, Missouri.
  • Reed, D., Ritchie, J.C., Carroll, B.C., et al. (1990). Implications of simultaneous monitoring of plasma dexamethasone levels for the DST. Neuroendocrinology Letters, 12(4):261; XXI Congress of the International Society of Psychoneuroendocrinology, Buffalo/Niagara Falls, New York.
  • Ritchie, J.C., Scotch, R.L., Walker, J.T., et al. (1989). Human growth hormone response to ovine corticotropin-releasing factor. Society for Neuroscience Abstracts, 15(2):1373, l9th Annual Meeting, Phoenix, Arizona.
  • Nishita, J.K., Ellinwood, E.H., Rockwell, W.J.K., Ritchie, J.C., et al. (1988). A new chronic starvation paradigm in the developing female rate: Implications for the study of anorexia nervosa. 43rd Annual Meeting Society of Biological Psychiatry, Montreal, Ouebec, Canada.
  • Davis, M.D., Nemeroff, C.B., Ritchie, J.C. (1988). Dynamics of concomitant CRF, AVP and ACTH secretion from perfused hypothalamic hypophyseal explants in vitro after electrical stimulation and drug infusion. Annual Meeting of the Endocrine Society.
  • Nishita, J.K., Ellinwood, E.H., Rockwell, W.J.K., Ritchie, J.C., et al. (1988). Stress-related effects of long-term caloric restriction on plasma corticosterone and vasopressin in the female rat: A new methodological apparatus. Society for Neuroscience Abstracts 14(1):444, 18th Annual Meeting, Toronto, Ontario, Canada.
  • Ritchie, J.C., Liu, P.K., Bissette, G., et al. (1988). A practical radioimmunoassay for plasma corticotropin releasing factor. Society for Neuroscience Abstracts, 14(2): 1286, 18th Annual Meeting, Toronto, Ontario, Canada.
  • Ritchie, J.C., Scotch, R.L., Walker, J.T., et al. (1989). Human growth hormone response to ovine corticotropin-releasing factor. Society for Neuroscience Abstracts, 15(2):1373, l9th Annual Meeting, Phoenix, Arizona.
  • Nishita, J.K., Ellinwood, E.H., Rockwell, W.J.K., Ritchie, J.C., et al. (1988). A new chronic starvation paradigm in the developing female rate: Implications for the study of anorexia nervosa. 43rd Annual Meeting Society of Biological Psychiatry, Montreal, Ouebec, Canada.
  • Davis, M.D., Nemeroff, C.B., Ritchie, J.C. (1988). Dynamics of concomitant CRF, AVP and ACTH secretion from perfused hypothalamic hypophyseal explants in vitro after electrical stimulation and drug infusion. Annual Meeting of the Endocrine Society.
  • Nishita, J.K., Ellinwood, E.H., Rockwell, W.J.K., Ritchie, J.C., et al. (1988). Stress-related effects of long-term caloric restriction on plasma corticosterone and vasopressin in the female rat: A new methodological apparatus. Society for Neuroscience Abstracts 14(1):444, 18th Annual Meeting, Toronto, Ontario, Canada.
  • Ritchie, J.C., Liu, P.K., Bissette, G., et al. (1988). A practical radioimmunoassay for plasma corticotropin releasing factor. Society for Neuroscience Abstracts, 14(2): 1286, 18th Annual Meeting, Toronto, Ontario, Canada.
  • Lee, J., Mitsushio, H., Paris, J.M., Lorens, S.A., Ritchie, J.C., et al. (1987). Differential behavioral and endocrine effects produced by intra-raphe administration of the neurokinin agonist DiMe C7, and the GABA agonist, Muscimol. Society for Neuroscience Abstracts, 13(1):613, 17th Annual Meeting, New Orleans, Louisiana.
  • Ritchie, J.C., Liu, P.K., Nemeroff, C.B., et al. (1987). Simultaneous determination of CRF and ACTH release from hypothalamic-pituitary blocks perfused in vitro: Responses to physiological and pharmacological manipulation. Society for Neuroscience Abstracts, 13(2):1371, 17th Annual Meeting, New Orleans, Louisiana.
  • Ritchie, J.C., O'Ouinn, A.N., Hodges, K.V., et al. (1987). Plasma dexamethasone concentrations in children and adolescents during the dexamethasone suppression test (DST). Society of Biological Psychiatry, 42nd Annual Meeting, Chicago, Illinois.
  • Ritchie, J.C., Kegelmeyer, A.E., Walker, J.T., et al. (1987). Comparison of plasma cortisol determinations by the Abbott TDx and C.P.B. methodology, for use in the dexamethasone suppression test (DST). Clin. Chem., 33(6):959, American Association for Clinical Chemistry, 40th Annual Meeting, San Francisco, California, 1987.
  • Ritchie, J.C., Liu, P.K., Nemeroff, C.B., et al. (1987). Simultaneous determination of CRF and ACTH release from hypothalamic-pituitary blocks perfused in vitro: Responses to physiological and pharmacological manipulation. Society for Neuroscience Abstracts, 13(2):1371, 17th Annual Meeting, New Orleans, Louisiana.
  • Lee, J., Mitsushio, H., Paris, J.M., Lorens, S.A., Ritchie, J.C., et al. (1987). Differential behavioral and endocrine effects produced by intra-raphe administration of the neurokinin agonist DiMe C7, and the GABA agonist, Muscimol. Society for Neuroscience Abstracts, 13(1):613, 17th Annual Meeting, New Orleans, Louisiana.
  • Johnson, K.L., Anderson, C.M., Nishita, J.K., Ritchie, J.C., et al. (1987). The distribution and dynamics of epinephrine-containing neurons in the rat brain: Influence of adrenocortical state. Society for Neuroscience Abstracts, 13(1):478, 17th Annual Meeting, New Orleans, Louisiana.
  • Ellinwood, E.H., Nishita, J.K., Kuhn, C.M., Ritchie, J.C., et al. (1987). Cocaine effects on plasma vasopressin, corticosterone and prolactin in the rat: Time course following acute injection. Society for Neuroscience Abstracts, 13(1):85, 17th Annual Meeting, New Orleans, Louisiana.
  • Johnson, K.L., Anderson, C.M., Nishita, J.K., Ritchie, J.C., et al. (1987). The distribution and dynamics of epinephrine-containing neurons in the rat brain: Influence of adrenocortical state. Society for Neuroscience Abstracts, 13(1):478, 17th Annual Meeting, New Orleans, Louisiana.
  • Ellinwood, E.H., Nishita, J.K., Kuhn, C.M., Ritchie, J.C., et al. (1987). Cocaine effects on plasma vasopressin, corticosterone and prolactin in the rat: Time course following acute injection. Society for Neuroscience Abstracts, 13(1):85, 17th Annual Meeting, New Orleans, Louisiana.
  • Ritchie, J.C., O'Ouinn, A.N., Hodges, K.V., et al. (1987). Plasma dexamethasone concentrations in children and adolescents during the dexamethasone suppression test (DST). Society of Biological Psychiatry, 42nd Annual Meeting, Chicago, Illinois.
  • Ritchie, J.C., Kegelmeyer, A.E., Walker, J.T., et al. (1987). Comparison of plasma cortisol determinations by the Abbott TDx and C.P.B. methodology, for use in the dexamethasone suppression test (DST). Clin. Chem., 33(6):959, American Association for Clinical Chemistry, 40th Annual Meeting, San Francisco, California, 1987.
  • Chappell, P.B., Smith, M.A., Ritchie, J.C., et al. (1986). Effects of corticotropin releasing factor on plasma ACTH and cortisol concentrations in schizophrenia. Society for Neuroscience Abstracts, 12(2): 1441, 16th Annual Meeting, Washington, D.C.
  • Chappell, P.B., Smith, M.A., Ritchie, J.C., et al. (1986). Effects of corticotropin releasing factor on plasma ACTH and cortisol concentrations in schizophrenia. Society for Neuroscience Abstracts, 12(2): 1441, 16th Annual Meeting, Washington, D.C.
  • Shun Wei, Li, Ritchie, J.C., Carroll, B.J. (1986). Plasma corticosterone and dexamethasone suppression test normalization. Society of Biological Psychiatry, 41st Annual Meeting, Washington, D.C.
  • Ritchie, J.C., Manepalli, A.N., France, R.D., Nemeroff, C.B., Carroll, B.J. (1986). What is the relationship between ACTH and cortisol dissociation in depression. American Psychiatric Association Annual Meeting, Washington, D.C.
  • Manepalli, A.N., Ritchie, J.C., Rayasam, K., et al. (1986). GRH stimulation test in depression. American Psychiatric Association Annual Meeting, Washington, D.C.
  • Belkin, B.M., Ritchie, J.C., Rayasam, K., et al. (1986). Plasma dexamethasone concentrations and the dexamethasone suppression test. Society for Neuroscience Abstracts, 12(1):606, 16th Annual Meeting, Washington, D.C.
  • Ritchie, J.C., Owens, M.J., O'Connor, L.W., et al. (1986). Measurement of ACTH and CRF immunoreactivity in adrenal gland and lymphocytes. Society for Neuroscience Abstracts, 12(2): 1041, 16th Annual Meeting, Washington, D.C.
  • Nemeroff, C.B., Krishnan, K.R.R., Owens, M.J., Bissette, G., Manepalli, A.N., Ritchie, J.C., et al. (1986). Growth hormone releasing factor: Endocrine and cerebrospinal fluid studies. Society for Neuroscience Abstracts, 12(1): 566, 16th Annual Meeting, Washington, D.C.
  • Nemeroff, C.B., Krishnan, K.R.R., Owens, M.J., Bissette, G., Manepalli, A.N., Ritchie, J.C., et al. (1986). Growth hormone releasing factor: Endocrine and cerebrospinal fluid studies. Society for Neuroscience Abstracts, 12(1): 566, 16th Annual Meeting, Washington, D.C.
  • Ritchie, J.C., Owens, M.J., O'Connor, L.W., et al. (1986). Measurement of ACTH and CRF immunoreactivity in adrenal gland and lymphocytes. Society for Neuroscience Abstracts, 12(2): 1041, 16th Annual Meeting, Washington, D.C.
  • Belkin, B.M., Ritchie, J.C., Rayasam, K., et al. (1986). Plasma dexamethasone concentrations and the dexamethasone suppression test. Society for Neuroscience Abstracts, 12(1):606, 16th Annual Meeting, Washington, D.C.
  • Shun Wei, Li, Ritchie, J.C., Carroll, B.J. (1986). Plasma corticosterone and dexamethasone suppression test normalization. Society of Biological Psychiatry, 41st Annual Meeting, Washington, D.C.
  • Ritchie, J.C., Manepalli, A.N., France, R.D., Nemeroff, C.B., Carroll, B.J. (1986). What is the relationship between ACTH and cortisol dissociation in depression. American Psychiatric Association Annual Meeting, Washington, D.C.
  • Manepalli, A.N., Ritchie, J.C., Rayasam, K., et al. (1986). GRH stimulation test in depression. American Psychiatric Association Annual Meeting, Washington, D.C.
  • Krishnan, K.R.R., Ritchie, J.C., Manepalli, A.N., et al. (1985). What is the relationship between ACTH and cortisol in normal and depressed patients. American College of Neuropsychopharmacology Annual Meeting.
  • Krishnan, K.R.R., Carroll, B.J., Manepalli, A.N., France, R.D., Ritchie, J.C., Nemeroff, C.B. (1985). Physiology of human HPA regulation, IV World Congress of Biological Psychiatry.
  • Ritchie, J.C., Keglemeyer, A.E., Walker, J.T. (1985). Performance of two non-extracted radioimmunoassays for plasma ACTH compared with two reference laboratory assays. Society for Neuroscience Abstracts, 11(1): 545, l5th Annual Meeting, Dallas, Texas.
  • Krishnan, K.R.R., Ritchie, J.C., Manepalli, A.N., et al. (1985). What is the relationship between ACTH and cortisol in normal and depressed patients. American College of Neuropsychopharmacology Annual Meeting.
  • Ritchie, J.C., Keglemeyer, A.E., Walker, J.T. (1985). Performance of two non-extracted radioimmunoassays for plasma ACTH compared with two reference laboratory assays. Society for Neuroscience Abstracts, 11(1): 545, l5th Annual Meeting, Dallas, Texas.
  • Krishnan, K.R.R., Carroll, B.J., Manepalli, A.N., France, R.D., Ritchie, J.C., Nemeroff, C.B. (1985). Physiology of human HPA regulation, IV World Congress of Biological Psychiatry.
  • Castor, C.W., Scott, M.E., Ritchie, J.C. (1971). Pharmacologic regulation of mitogenesis induced by a platelet mediator. XIV International Congress of Rheumatology.
  • Castor, C.W., Scott, M.E., Ritchie, J.C. (1971). Pharmacologic regulation of mitogenesis induced by a platelet mediator. XIV International Congress of Rheumatology.
  • Castor, C.W., Wright, D., Ritchie, J.C. (1969). Connective tissue regulation. J. Lab and Clin. Med. Abstract, 74:860.
  • Castor, C.W., Wright, D., Ritchie, J.C. (1969). Connective tissue regulation. J. Lab and Clin. Med. Abstract, 74:860.