Urologic Pathology

Second opinions on urologic pathology cases are performed by -

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Adeboye O Osunkoya, MD

Assistant Professor
Pathology & Laboratory Medicine

Other Appointments/Positions

Assistant Professor of Urology, Emory University School of Medicine

Director, Genitourinary Pathology, Emory University School of Medicine

Pathology Division(s):
Anatomic Pathology

Email Address:
adeboye.osunkoya@emoryhealthcare.org

Education:

MBBS   University of Ibadan College of Medicine, Oyo State, Nigeria, - 1998

  Intern, University College Hospital, Ibadan, - 1999

  Research Fellow, Institute of Child Health, University College Hospital, Ibadan, - 2000

  Resident, Anatomic and Clinical Pathology, University College Hospital, Ibadan, 2000 - 2002

  Resident, Anatomic and Clinical Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 2002 - 2004

  Chief Resident, Anatomic and Clinical Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 2004 - 2006

  Clinical and Research Fellow, Division of Genitourinary Pathology, The Johns Hopkins Hospital, Baltimore, MD, 2006 - 2007

Research Interests:

- Urologic Pathology
My research interests are mainly in the field of genitourinary pathology. I have great interest in tumors of the prostate, urinary bladder, kidney and testis.

Clinical Focus:

My clinical focus is in surgical pathology with major emphasis on genitourinary pathology. I sign out general surgical pathology cases and frozen sections at both Emory University Hospital and the Veterans Affairs Medical Center. I also sign out autopsies, gynecologic and non-gynecologic cytology cases at the latter. I handle in house genitourinary pathology consultation cases from Emory University Hospital, Veterans Affairs Medical Center, Emory Midtown Hospital, Grady Hospital and Children's Healthcare of Atlanta at Egleston and Scottish Rite. In addition, I offer expert consultation from outside institutions in the area of genitourinary pathology (please see separate website link). I have a secondary appointment in the department of Urology and I am active in their weekly tumor boards at both the Emory University Hospital and the Veterans Affairs Medical Center.

Honors / Awards:

Young Investigator Award in Clinical Research, Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD

Perry Lambird Award, Outstanding Resident in Clinical Pathology, University of Oklahoma Health Sciences Center, OK

Donald West King Fellow, Gastrointestinal Pathology Division, Armed Forces Institute of Pathology, Washington, DC

Parker-Heartland Award, Outstanding Resident in Anatomic Pathology, University of Oklahoma Health Sciences Center,OK

Member, Residents Council, University of Oklahoma Health Sciences Center, OK

Nancy K. Hall Award for Most Outstanding First Year Resident, Department of Pathology, University of Oklahoma Health Sciences Center, OK

Specialty Boards:

Aug 2006  Anatomic and Clinical Pathology

Selected Publications:

Published and Accepted Research Articles -

Arnold RS, Sun CQ, Richards JC, Grigoriev G, Coleman IM, Nelson PS, Hsieh CL, Lee JK, Xu Z, Rogatko A, Osunkoya AO, Zayzafoon M, Chung L, Petros JA. Mitochondrial DNA mutation stimulates prostate cancer growth in bone stromal environment. Prostate. 2009 Jan 1;69(1):1-11.

Osunkoya AO, Cohen C, Lawson D, Picken MM, Amin MB, Young AN. Claudin-7 and Claudin-8: Immunohistochemical Markers for the Differential Diagnosis of Chromophobe Renal Cell Carcinoma and Oncocytoma. Hum Pathol. 2009 Feb;40(2):206-10.

Gupta R, Balzer B, Picken M, Osunkoya AO, Shet T, Alsabeh R, Luthringer D, Paner G, Amin MB. Diagnostic Implications of Transcription Factor Pax 2 Protein & Transmembrane Enzyme Complex Carbonic Anhydrase IX Immunoreactivity in Adult Renal Epithelial Neoplasms. Am J Surg Pathol. 2009 Feb;33(2):241-7.

Nigwekar P, Tamboli P, Amin MB, Osunkoya AO, Ben-Dor D, Amin MB. Plasmacytoid urothelial carcinoma: detailed analysis of morphology with clinicopathologic correlation in 17 cases. Am J Surg Pathol. 2009 Mar;33(3):417-24.

Bong GW, Ritenour CW, Osunkoya AO, Smith MT, Keane TE. Evaluation of modern pathological criteria for positive margins in radical prostatectomy specimens and their use for predicting biochemical recurrence. BJU Int. 2009 Feb;103(3):327-31.

Osunkoya AO, Hansel DE, Sun X, Netto GJ, Epstein JI. Aberrant Diffuse Expression of p63 in Adenocarcinoma of the Prostate on Needle Biopsy and Radical Prostatectomy: Report of 21 Cases. Am J Surg Pathol. 2008 Mar;32(3):461-467.

Osunkoya AO, Nielsen ME, Epstein JI. Prognosis of Mucinous Adenocarcinoma of the Prostate Treated by Radical Prostatectomy: A Study of 47 Cases. Am J Surg Pathol. 2008 Mar; 32(3):468-472.

Landrum LM, Rutledge TL, Osunkoya AO, Mannel R. Uterine leiomyoma with associated pseudo-Meigs syndrome mimicking ovarian carcinoma. JOSMA 2008 Feb; 101(2):38-9.

Osunkoya AO, Adsay NV, Cohen C, Epstein JI, Smith SL. MUC2 expression in primary mucinous and nonmucinous adenocarcinoma of the prostate: an analysis of 50 cases on radical prostatectomy. Mod Pathol. 2008 Jul; 21(7):789-94.

Osunkoya AO, Carter HB, Epstein JI. A clinicopathologic study of preoperative and postoperative findings with minute Gleason 3+3=6 cancer at radical prostatectomy. Urology. 2008 Sep;72(3):638-40.

Yoon GS, Wang W, Osunkoya AO, Lane Z, Partin AW, Epstein JI. Residual tumor potentially left behind after local ablation therapy in prostate adenocarcinoma. J Urol. 2008 Jun; 179(6):2203-6.

Graham TR, Zhau HE, Odero-Marah VA, Osunkoya AO, Kimbro KS, Tighiouart M, Liu T, Simons JW, O'Regan RM. Insulin-like growth factor-I-dependent up-regulation of ZEB1 drives epithelial-to-mesenchymal transition in human prostate cancer cells. Cancer Res. 2008 Apr 1; 68(7):2479-88.

Osunkoya AO, Hansel DE, Parwani AV, Ali TZ, Tamas EF, Untawale VG, Kahane H, Epstein JI. The Symphony" Protocol for H&E Staining of Prostatic Adenocarcinoma on Needle Biopsy: A Multicenter Analysis of 120 cases. Pathology. 2008 Aug; 40(5):450-456.

Scharer CD, Laycock N, Osunkoya AO, Logani S, McDonald JF, Benigno BB, Moreno CS. Aurora kinase inhibitors synergize with paclitaxel to induce apoptosis in ovarian cancer cells. J Transl Med. 2008 Dec 11; 6:79.

Tophkhane C, Yang S, Bales W, Archer L, Osunkoya A, Thor AD, Yang X. Bcl-2 overexpression sensitizes MCF-7 cells to genistein by multiple mechanisms. Int J Oncol. 2007 Oct;31(4):867-74.

Osunkoya AO, Netto GJ, Epstein JI. Colorectal adenocarcinoma involving the prostate: report of 9 cases. Hum Pathol. 2007 Dec;38(12):1836-41.

Osunkoya AO, Epstein JI. Primary mucin-producing urothelial-type adenocarcinoma of prostate: report of 15 cases. Am J Surg Pathol. 2007 Sep;31(9):1323-9.

Kharfan-Dabaja MA, Patel SA, Osunkoya AO, Kojouri K, Kamble R, Yang J, Hashmi M, Ozer H, Selby GB. Expression of the vascular endothelial growth factor receptors 1 and 2 in acute myeloid leukemia: incidence and feasibility of immunohistochemical staining. Clin Lab Haematol. 2006 Aug;28(4):254-8.

Osunkoya AO, Agte SD, Laszik Z. A 67-year-old woman with chronic proteinuria. Focal segmental and global glomerulosclerosis with light microscopic and ultrastructural features consistent with Fabry disease. Arch Pathol Lab Med. 2006 Jun;130(6):e93-5.

Akang E.E.U., Kuti MA, Osunkoya A.O., Malomo A.O., Shokunbi M.T., Amutta S.B.: Pattern of fatal head injuries in Ibadan - a ten year review. Med Sci Law 2002 Apr;42(2):160-6.

Book Chapters -

Thor AD, Osunkoya AO. Chapter 19 (The Breast) Rubin's Pathology Clinicopathologic Foundations of Medicine. 5th Edition. Published March 2007.

Other Publications -

Amin MB, Gupta R, Osunkoya AO, Hes O, Billis A, Bacchi CE, Hansel D, Zhou M, deCastro MG, Moch H, Salles P, Cabrera RA, Gown AM. Carcinoma of Collecting Ducts of Bellini: Analysis of 27 Distinctive Cases of Renal Cell Carcinoma with Aggressive Clinical Behavior. Mod Pathol 2009; 22: 157A.

Lotan TL, Osunkoya AO, DeMarzo AM, Netto GJ, Epstein JI. Prostate Adenocarcinomas Aberrantly Expressing p63 Have a Luminal Cell Phenotype. Mod Pathol 2009; 22: 180A.

Netto GJ, Wang W, Brownlee NA, Osunkoya AO, Hicks J, Sharma R, Albadine R. PAX8 (+)/p63 (-) Immunostaining Pattern in Renal Collecting Duct Carcinoma (CDC): A Useful Immunoprofile in the Differential Diagnosis of CDC vs Urothelial Carcinoma of Upper Urinary Tract. Mod Pathol 2009; 22: 186A.

Young AN, Yin-Goen Q, Phan JH, Moffitt R, Wang MD, Osunkoya AO. Novel Immunohistochemical Biomarkers for Renal Cell Carcinoma Derived from Expression Microarray Data. Mod Pathol 2009; 22: 202A.

Moreno CS, Henderson VM, Zhou W, Williams D, Laycock N, Kitayama H, Osunkoya AO. RAP1 Signaling in Prostate Cancer Progression. Mod Pathol 2009; 22: 185A.

Osunkoya AO, Young AN, Wang W, Netto GJ, Epstein JI. Comparison of Gene Expression Profiles in Tubulocystic Carcinoma and Collecting Duct Carcinoma of the Kidney. Mod Pathol 2009; 22: 187A.

Schniederjan SD, Osunkoya AO. Lymphomas of the Genitourinary Tract: A Clinicopathologic Study of 40 Cases. Mod Pathol 2009; 22: 192A.

Lim M, Adsay NV, Grignon DJ, Osunkoya AO. Urothelial Carcinoma with Divergent Villoglandular Differentiation: A Study of 14 Cases. Mod Pathol 2009; 22:179A.

Jani JC, Cohen C, Jehnazeb K, Lawson D, Osunkoya AO. Neuroendocrine, Proliferative and Apoptotic Markers in Prostatic Adenocarcinoma and Small Cell Carcinoma of the Prostate: A Tissue Microarray Analysis of 64 Cases. Mod Pathol 2009; 22: 174A.

Osunkoya AO, Nielsen ME, Epstein JI. Prognosis of Mucinous Adenocarcinoma of the Prostate Treated by Radical Prostatectomy: A Study of 47 Cases. Modern Pathology 2008; 21(1S): 175A.

Osunkoya AO, Hansel DE, Sun X, Netto GJ, Epstein JI. Aberrant Diffuse Expression of p63 in Adenocarcinoma of the Prostate on Needle Biopsy and Radical Prostatectomy: Report of 21 cases. Modern Pathology 2008; 21(1S): 174A-175A.

Smith SL, Adsay NV, Cohen C, Epstein JI, Smith SL. Osunkoya AO. MUC2 Expression in Primary Mucinous and Nonmucinous Adenocarcinoma of the Prostate: An analysis of 50 cases on radical prostatectomy. Modern Pathology 2008; 21(1S): 182A.

Yoon GS, Wang W, Osunkoya AO, Lane Z, Epstein JI. Residual Tumor Potentially Left Behind after Local Ablation Therapy in Prostate Adenocarcinoma. Modern Pathology 2008; 21(1S): 192A.

Young AN, Cohen C, Lawson D, Picken MM, Amin MB, Osunkoya AO. Claudin-7 and Claudin-8: Immunohistochemical Markers for the Differential Diagnosis of Chromophobe Renal Cell Carcinoma and Oncocytoma. Modern Pathology 2008; 21(1S): 192A.

Osunkoya AO, Epstein JI. Primary Mucin-Producing Urothelial-Type Adenocarcinoma of Prostate: Report of 15 Cases. Modern Pathol 2007; 20(2):167A.

Osunkoya AO, Hansel DE, Parwani AV, Ali TZ, Tamas EF, Untawale VG, Kahane H, Epstein JI. The Symphony" Protocol for H&E Staining of Prostatic Adenocarcinoma on Needle Biopsy: A Multicenter Analysis of 120 cases Modern Pathol 2007; 20(2):167A-168A.

Osunkoya AO, Netto GJ, Epstein JI. Colorectal Adenocarcinoma Involving the Prostate: Report of 9 Cases. Modern Pathol 2007; 20(2):167A.

Osunkoya AO, Truong C.D., Laszik Z.G.: TM but not EPCR Expression is Reduced in The Tubulointerstitial Capillaries of Patients with Proliferative and Membranous Lupus Nephritis. Lab Invest. 2006 Jan; 86(1):264A-265A.

Thor AD, Osunkoya AO. Giant Juvenile Fibroadenoma (GJF). American Society for Breast Disease (ASBD) Expert Advisor commentaries. May 2005.

Osunkoya AO, Foster T. and Pitha J. Ectopic Meningothelial Hamartoma of the Scalp. J Cutan Pathol 2005: 32: 107A.

Osunkoya AO, Aronson W, Kern W, Vogel S, Dunn T: Cavernous transformation of the portal vein in a patient with 50% reduction in Protein C, probable polycythemia vera and MTHFR C677T point mutation. Modern Pathol 2003;16(1):6A.